Most patients will have their stem cell transplant in an inpatient unit and stay in the hospital for about 4 weeks.ДЄllogeneic blood and marrow transplants treat conditions such as cancers of the blood and bone marrow (for example:В leukemia, myelodysplastic syndrome, myelofibrosis and lymphoma). After being collected, the donor's stem cells are infused into you after you are given high-dose chemotherapy and (usually) radiation treatment. Stem cells are collected from the bone marrow or peripheral blood of a donor and areВ used to help treat patients when chemotherapy treatment alone вЂ‹is not likely to be effective.ДЄllogeneic blood and marrow transplant is when stem cells areВ collected from a living donor (not yourself) who may be a blood relativeВ or an unrelated volunteer donor from a global registry. These transplantsВ are used for patients who have blood orВ bone marrow disorders and other types of conditions that may benefit from this treatment. This stands for donor lymphocyte infusion.Blood and marrow transplants are also known as hematopoietic stem cell transplants. This boost helps the body to fight existing cancer cells more effectively. They come directly from the stem cell donor. During this process, you may receive lymphocytes. The stem cells work to destroy the existing cancer cells. Then, the immune system attacks the few remaining cancer cells. In previous methods mentioned, the transplant leads to a boost in the immune system. It means the stem cells are working to destroy the cancer cells in the body. However, this process can cause graft versus tumor effect. This is the same basic process as other methods. At this point, the cells begin to engraft. The doctors then transplant the stem cells from the donor. It also helps to stop rejection from occurring. Doctors will work to keep the personвЂ™s immune system suppressed.

The second component is the use of immune system suppression. This means the drugs work to reduce some of the patientвЂ™s bone marrow. As noted, the condition treatment often creates the biggest risks for patients. The process starts with chemotherapy, but at a much lower dose.

Some locations offer a mini-transplant procedure. A match occurs when the tissue type and blood sample match. They then compare the stem cells in each. Doctors extract tissue samples from both the patient and the donor. The proteins are in a personвЂ™s white blood cells, as well as tissues. This process involves the use of human leukocyte antigens. To determine the match, tissue typing occurs. These are banks of people who sign up to act as a donor. In these cases, it can help a person to get the care they need.Дoctors have access to donor registries. Some donate it to a public cord blood bank, while others store it privately for a fee. However, more people are banking umbilical cord blood today.

A final option is an unrelated umbilical cord blood match. However, unrelated people may still be an option. It is possible to find a very specific, targeted stem cell match in an unrelated donor. A sibling or family member is the most likely option. Doctors can include any person who has an HLA-match. The closer the match, the more likely the procedure will be effective.ДЄ successful match can happen from various donors. It is important for doctors to match the donor and patient as closely as possible. How effective depends on how well the stem cells match.

Allogeneic stem cell transplant